Synthesis of a new δ-lactone bridged apovincamine derivative

Gábor Nárai, P. Sohár, A. Csámpai, Béla Zsadon

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Starting from (+)-17,18-dehydroapovincamine, a new δ-lactone bridged apovincamine derivative (6) was synthesized in two steps involving oxidative hydroboration followed by catalytic hydrogenation. The structure elucidation of this compound, the intermediate and the by-products was performed by IR, 1H- and 13C-NMR methods including DNOE measurements.

Original languageEnglish
Pages (from-to)151-152
Number of pages2
JournalHeterocycles
Volume48
Issue number1
Publication statusPublished - 1998

Fingerprint

Hydrogenation
Lactones
Byproducts
Nuclear magnetic resonance
Derivatives
apovincamine
Proton Magnetic Resonance Spectroscopy
Carbon-13 Magnetic Resonance Spectroscopy

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of a new δ-lactone bridged apovincamine derivative. / Nárai, Gábor; Sohár, P.; Csámpai, A.; Zsadon, Béla.

In: Heterocycles, Vol. 48, No. 1, 1998, p. 151-152.

Research output: Contribution to journalArticle

Nárai, Gábor ; Sohár, P. ; Csámpai, A. ; Zsadon, Béla. / Synthesis of a new δ-lactone bridged apovincamine derivative. In: Heterocycles. 1998 ; Vol. 48, No. 1. pp. 151-152.
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