Synthesis of 5-Carboxamidotriazoles via Azide-Alkyne Cycloaddition–Aminocarbonylation Sequence

Péter Szuroczki, Judit Sámson, L. Kollár

Research output: Contribution to journalArticle

Abstract

5-Carboxamidotriazoles were prepared in the palladium-catalyzed aminocarbonylation of the corresponding iodotriazole using various amines as N-nucleophiles under mild reaction conditions. The iodoheteroarene substrates were obtained in good yields in copper-catalysed azide-alkyne cycloaddition of iodoalkynes (2′-iodophenylacetylene and ethyl iodopropiolate) and benzyl azide.

Original languageEnglish
Pages (from-to)5527-5530
Number of pages4
JournalChemistrySelect
Volume4
Issue number19
DOIs
Publication statusPublished - May 24 2019

Fingerprint

Alkynes
Azides
Nucleophiles
Cycloaddition
Palladium
Amines
Copper
Substrates

Keywords

  • carbon monoxide
  • carbonylation
  • cycloaddition
  • iodoalkyne
  • palladium

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis of 5-Carboxamidotriazoles via Azide-Alkyne Cycloaddition–Aminocarbonylation Sequence. / Szuroczki, Péter; Sámson, Judit; Kollár, L.

In: ChemistrySelect, Vol. 4, No. 19, 24.05.2019, p. 5527-5530.

Research output: Contribution to journalArticle

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