Synthesis of 4‐Aminopyrimidines from 1,2,4‐Oxadiazoles, III A Novel Type of Formation of Olefins from Amines

Dezsö Korbonits, Kálmán Simon, P. Kolonits

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

On heating at 100°C, 1,2,3,4‐tetrahydro‐6,7‐dialkoxy‐1‐[(acylamidino)methylene]isoquinolines (5) are transformed into 4‐substituted 6,7‐dihydro‐9,10‐dialkoxy‐2H‐pyrimido[6,1‐α]isoquinoline‐2‐imines (6), while at 140°C they undergo a novel prototropic rearrangement via 6 to give 4‐amino‐6‐(4,5‐dialkoxy‐2‐vinylphenyl)‐2‐phenylpyrimidines (7). The structure of 7a has been determined by X‐ray analysis.

Original languageEnglish
Pages (from-to)111-113
Number of pages3
JournalChemische Berichte
Volume124
Issue number1
DOIs
Publication statusPublished - 1991

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Isoquinolines
Alkenes
Amines
Heating

Keywords

  • 4‐Aminopyrimidines
  • Olefin formation
  • Pyrimido[6,1‐α]isoquinolines

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis of 4‐Aminopyrimidines from 1,2,4‐Oxadiazoles, III A Novel Type of Formation of Olefins from Amines. / Korbonits, Dezsö; Simon, Kálmán; Kolonits, P.

In: Chemische Berichte, Vol. 124, No. 1, 1991, p. 111-113.

Research output: Contribution to journalArticle

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