Synthesis of 4,5-dihydro-1,4-benzothiazepine derivatives via ring expansion

Research output: Contribution to journalArticle

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Abstract

Basic treatment in methanol of a chloro-β-lactam fused with dihydrobenzothiazine led to the corresponding 1,4-benzothiazepine derivative via a new ring expansion. The structure of the product, deduced from IR and 1H NMR data, was confirmed by X-ray measurements.

Original languageEnglish
Pages (from-to)5077-5078
Number of pages2
JournalTetrahedron Letters
Volume22
Issue number50
DOIs
Publication statusPublished - 1981

Fingerprint

Lactams
Methanol
Nuclear magnetic resonance
X-Rays
Derivatives
X rays
Proton Magnetic Resonance Spectroscopy

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of 4,5-dihydro-1,4-benzothiazepine derivatives via ring expansion. / Fodor, L.; Szabó, J.; Bernáth, G.; Párkányí, L.; Sohár, P.

In: Tetrahedron Letters, Vol. 22, No. 50, 1981, p. 5077-5078.

Research output: Contribution to journalArticle

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abstract = "Basic treatment in methanol of a chloro-β-lactam fused with dihydrobenzothiazine led to the corresponding 1,4-benzothiazepine derivative via a new ring expansion. The structure of the product, deduced from IR and 1H NMR data, was confirmed by X-ray measurements.",
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AU - Szabó, J.

AU - Bernáth, G.

AU - Párkányí, L.

AU - Sohár, P.

PY - 1981

Y1 - 1981

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AB - Basic treatment in methanol of a chloro-β-lactam fused with dihydrobenzothiazine led to the corresponding 1,4-benzothiazepine derivative via a new ring expansion. The structure of the product, deduced from IR and 1H NMR data, was confirmed by X-ray measurements.

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