Synthesis of 3,6-branched arabinogalactan-type tetra- and hexasaccharides for characterization of monoclonal antibodies

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Abstract

Synthesis of tetra- and hexasaccharides built up from a β-(1→6)-linked galactopyranosyl backbone with arabinofuranosyl side chains at position 3 and with a 3-aminopropyl spacer related to arabinogalactans is described. These oligosaccharides were prepared for investigation of monoclonal antibodies raised against arabinogalactan proteins (AGPs) from pressed juice of Echinacea purpurea.

Original languageEnglish
Pages (from-to)1434-1441
Number of pages8
JournalCarbohydrate Research
Volume344
Issue number12
DOIs
Publication statusPublished - Aug 17 2009

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Keywords

  • Arabinogalactan proteins
  • Monoclonal antibodies
  • Oligosaccharide synthesis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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