Synthesis and utilization of the Bis(>P(O)CH2)amine derivatives obtained by the double Kabachnik-Fields reaction with cyclohexylamine; quantum chemical and X-ray study of the related bidentate chelate platinum complexes

Erika Bálint, Eszter Fazekas, György Pintér, Áron Szöllosy, Tamás Holczbauer, Mátyás Czugler, László Drahos, Tamás Körtvélyesi, György Keglevich

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The microwave-assisted double Kabachnik-Fields (phospha-Mannich) reaction of cyclohexylamine, two equivalents of paraformaldehyde and >P(O)H species, such as dialkyl phosphites, ethyl phenyl-H-phosphinate and diphenylphosphine oxide affords the title compounds in good yields. The bis(diphenylphosphinoxido) derivative was converted to the corresponding bidentate chelate platinum complex in two steps, whose stereostructure was elucidated by quantum chemical calculations. The crystal structure of the bidentate chelate complex was studied by X-ray analysis.

Original languageEnglish
Pages (from-to)547-554
Number of pages8
JournalCurrent Organic Chemistry
Volume16
Issue number4
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Bidentate chelate platinum complex
  • Kabachnik-fields reaction
  • N
  • N-bis(phosphorylmethyl)amine derivatives
  • Quantum chemical calculations
  • Stereostructure
  • X-ray crystallography

ASJC Scopus subject areas

  • Organic Chemistry

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