Cephalosporin C-3-phosphoranes have been converted into the corresponding 3-alkenylcephems and novel tricyclic derivatives on treatment with different bifunctional carbonyl compounds. The effect of substituants on the product ratio has been examined. The stereoselectivity of the ring-closure is explained on the basis of theoretical considerations.
|Number of pages||4|
|Journal||Journal of the Chemical Society, Perkin Transactions|
|Publication status||Published - Dec 1 1994|
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