Synthesis and transformations of 3-vinylcephalosporins. Part 6. Reactions of cephalosporin phosphoranes with bifunctional carbonyl compounds

János Pitlik, Tamás E. Gunda, Gyula Batta, József Jekö

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Cephalosporin C-3-phosphoranes have been converted into the corresponding 3-alkenylcephems and novel tricyclic derivatives on treatment with different bifunctional carbonyl compounds. The effect of substituants on the product ratio has been examined. The stereoselectivity of the ring-closure is explained on the basis of theoretical considerations.

Original languageEnglish
Pages (from-to)3043-3046
Number of pages4
JournalJournal of the Chemical Society, Perkin Transactions
Issue number20
Publication statusPublished - Dec 1 1994


ASJC Scopus subject areas

  • Chemistry(all)

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