Synthesis and steric structure of cis‐ and trans‐alicycle‐fused dihydrothiazepines

P. Sohár, K. Újszászy, J. Szabó, L. Simon, G. S. Talpas, L. Fodor, G. Bernáth

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3 Citations (Scopus)

Abstract

β‐Lactam‐condensed saturated thiaazabicycles underwent ring transformation to give a new type of alicycle‐fused 3‐phenyl‐2‐methoxycarbonyl‐4,5‐dihydro‐1,4‐thiazepine. Oxidation of the cis and trans cyclohexane derivatives with perbenzoic acid furnished sulphones. The configurations and conformations of the new compounds were confirmed by 1H and 13C NMR spectroscopy, making use of DR, DNOE, DEPT and 2D HSC measurements.

Original languageEnglish
Pages (from-to)928-932
Number of pages5
JournalMagnetic Resonance in Chemistry
Volume29
Issue number9
DOIs
Publication statusPublished - Sep 1991

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Keywords

  • 2D HSC
  • Configurations H and C NMR
  • Conformational analysis
  • DEPT
  • DNOE
  • DR
  • Ring transformation of β‐lactam‐condensed saturated thiaazabicycles to alicycle‐fused 4,5‐dihydro‐1,4‐thiazepines
  • Structure
  • Synthesis

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)

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