Synthesis and steric structure of alicycle‐fused 1,3‐thiazine‐β‐lactams

Pál Sohár, János Szabó, Lajos Simon, Gizella S. Talpas, Erzsébet Szücs, Gábor Bernáth

Research output: Contribution to journalArticle

6 Citations (Scopus)


2 + 2‐Cycloaddition reactions of cis‐ and trans‐cyclopenta‐, ‐cyclohexa‐ and ‐cyclohepta‐ and trans‐cycloocta [e]‐2‐phenyl‐4H‐1,3‐thiazines gave new types of hydrated tricyclic 1,3‐thiazino‐β‐lactam derivatives having the 2‐phenyl substituent and H‐9 in cis positions. The configurations and conformations of the new compounds were determined by 1H and 13C NMR spectroscopy, including double resonance, DNOE and 2D HSC measurements.

Original languageEnglish
Pages (from-to)687-692
Number of pages6
JournalMagnetic Resonance in Chemistry
Issue number7
Publication statusPublished - Jul 1991



  • 2D‐HSC
  • Alicycle‐fused 1,3‐thiazino‐β‐lactams
  • Conformational analysis
  • Double resonance DNOF
  • H and C NMR spectra
  • Synthesis

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)

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