Synthesis and stereostructure of some 5,5′-disubstituted 3-acetyl-2,2′-BI-2H-1,3,4-oxa(thia)diazolines

László Somogyi, Mátyás Czugler, Pál Sohár

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The synthesis of some (methyl)glyoxal 1,2-bis(acylhydrazones) (1, 3-6) and their cyclization into the title compounds (7-10) under acetylating conditions are described. The stereostructures of the new bi-heterocyclic diastereomers were studied by 1H- and 13C-NMR measurements as well as by X-ray analysis.

Original languageEnglish
Pages (from-to)9355-9362
Number of pages8
JournalTetrahedron
Volume48
Issue number42
DOIs
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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