Spiropyrazolines have been synthesized by 1,3-dipolar cycloaddition of an 2-arylidene-1 -tetralone, 3-arylidene-chromanones, -1-thiochromanones, and -flavanones with diazomethane. The relative configuration and stereochemistry of the products have been determined by means of one-dimensional difference N.O.E. measurements. It is shown that ring-closure reaction is regioselective, yielding stereohomogeneous spiropyrazolines in one step.
|Number of pages||4|
|Journal||Journal of the Chemical Society, Perkin Transactions 2|
|Publication status||Published - Jan 1 1986|
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