Synthesis and photophysical properties of tetra- and pentaalkynylfluorobenzenes by Sonogashira reactions of novel iodofluorobenzenes

Muhammad Sharif, Aneela Maalik, Sebastian Reimann, Jamshed Iqbal, Tamás Patonay, Anke Spannenberg, Alexander Villinger, Peter Langer

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6 Citations (Scopus)

Abstract

1,2-Difluoro-3,4,5,6-tetraiodobenzene, 1,3-difluoro-2,4,5,6- tetraiodobenzene, 1,4-difluoro-2,3,5,6-tetraiodobenzene and 1-fluoro-2,3,4,5,6- pentaiodobenzene were prepared by oxidative iodination of fluorinated benzenes. Sonogashira cross-coupling reactions of these fluorinated periodobenzenes afforded fluorescent penta- and tetraalkynylfluorobenzenes in high yields.

Original languageEnglish
Pages (from-to)174-183
Number of pages10
JournalTetrahedron
Volume69
Issue number1
DOIs
Publication statusPublished - Jan 7 2013

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Keywords

  • Alkynes
  • Cross-coupling
  • Organofluorine compounds
  • Palladium
  • Sonogashira reaction

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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