Synthesis and lipase-catalyzed enantiotope selective acetylation of 2- benzoyloxy-1,3-propanediol

Viktória Bódai, Lajos Novák, László Poppe

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11 Citations (Scopus)

Abstract

Preparation and porcine pancreatic lipase (PPL)-catalyzed enantiotope selective acetylation of the prochiral 2-benzoyloxy-1,3-propanediol (1a) is described. The reaction with PPL and vinyl acetate gave monoacetate (2a) of 96 % e.e.

Original languageEnglish
Pages (from-to)759-761
Number of pages3
JournalSynlett
Issue number6
DOIs
Publication statusPublished - Jan 1 1999

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Keywords

  • 2-O-benzoylglycerol
  • Acetylation
  • Enantiotope selective
  • Lipase

ASJC Scopus subject areas

  • Organic Chemistry

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