Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743

P. Mátyus, E. Kasztreiner, E. Diesler, A. Behr, I. Varga, J. Kosary, G. Rabloczky, L. Jaszlits

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

[1,4]Benzodioxanylmethyl-, [1,4]benzodioxanylmethylaminopropyl- and phenoxyethylaminoethyl-substituted lactams were synthesised and their hypotensive activity was investigated. Some of these compounds show moderate to high hypotensive effect, but they had more toxic and/or side effects than GYKI-12 743.

Original languageEnglish
Pages (from-to)543-546
Number of pages4
JournalArchiv der Pharmazie
Volume327
Issue number9
Publication statusPublished - 1994

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Lactams
Poisons
GYKI 12743

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

Mátyus, P., Kasztreiner, E., Diesler, E., Behr, A., Varga, I., Kosary, J., ... Jaszlits, L. (1994). Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743. Archiv der Pharmazie, 327(9), 543-546.

Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743. / Mátyus, P.; Kasztreiner, E.; Diesler, E.; Behr, A.; Varga, I.; Kosary, J.; Rabloczky, G.; Jaszlits, L.

In: Archiv der Pharmazie, Vol. 327, No. 9, 1994, p. 543-546.

Research output: Contribution to journalArticle

Mátyus, P, Kasztreiner, E, Diesler, E, Behr, A, Varga, I, Kosary, J, Rabloczky, G & Jaszlits, L 1994, 'Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743', Archiv der Pharmazie, vol. 327, no. 9, pp. 543-546.
Mátyus P, Kasztreiner E, Diesler E, Behr A, Varga I, Kosary J et al. Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743. Archiv der Pharmazie. 1994;327(9):543-546.
Mátyus, P. ; Kasztreiner, E. ; Diesler, E. ; Behr, A. ; Varga, I. ; Kosary, J. ; Rabloczky, G. ; Jaszlits, L. / Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743. In: Archiv der Pharmazie. 1994 ; Vol. 327, No. 9. pp. 543-546.
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