Synthesis and enantioselective transport studies of both enantiomers of new chiral proton-ionizable crown ethers containing a diarylphosphinic acid unit

Hajnalka Szabó-Szentjóbi, Péter Bagi, Judit Müller, György Tibor Balogh, Tünde Tóth, Péter Huszthy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The synthesis of four new enantiopure crown ethers containing a diarylphosphinic acid unit has been carried out. As a continuation of our work in this field, the enantioselective transport ability of these ligands for chiral amines has been studied in an aqueous source phase/lipophilic organic bulk liquid membrane/aqueous receiving phase system controlled by the pH of the media. By altering the structures of the carriers we improved the enantioselectivity of the transport.

Original languageEnglish
Pages (from-to)1275-1281
Number of pages7
JournalTetrahedron
Volume75
Issue number9
DOIs
Publication statusPublished - Mar 1 2019

Keywords

  • Diarylphosphinic acids
  • Enantiomeric recognation
  • Enantioselective transport
  • Liquid membrane system
  • Proton-ionizable crown ethers

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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