Synthesis and conformational preferences of novel steroidal 16-spiro-1, 3, 2-dioxaphosphorinanes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The diastereomeric pairs a and b of novel 16-spiro-dioxaphosphorinanes 3-11 were synthesised via the phosphorylation of 16, 16-bis(hydroxymethyl)estrone 3-methyl ether (1) and its 17β-hydroxy analogue (2) and their stereostructures were investigated by different NMR methods.

Original languageEnglish
Pages (from-to)340-344
Number of pages5
JournalLetters in Organic Chemistry
Volume6
Issue number4
DOIs
Publication statusPublished - Jun 2009

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Phosphorylation
Nuclear magnetic resonance
estrone 3-methyl ether

Keywords

  • Dioxaphosphorinanes
  • Phosphorylations
  • Spiro compounds
  • Stereostructure
  • Steroids

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry

Cite this

Synthesis and conformational preferences of novel steroidal 16-spiro-1, 3, 2-dioxaphosphorinanes. / Frank, E.; Sipos, László; Wölfling, J.; Schneider, G.

In: Letters in Organic Chemistry, Vol. 6, No. 4, 06.2009, p. 340-344.

Research output: Contribution to journalArticle

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