Abstract
The steroidal pyrazine 5 has been synthesized from 5α-cholestane-2,3-dione, and its cd has been compared with that of octahydronaphtopyrazine 7 with C2-symmetry. The n→x* - Cotton effects of the parent compound have the same signs and magnitudes as for the homochirally analogous steroid, whereas the k→x* - Cotton effects differ. On the other hand, pyrazines containing substituents nonsymmetrically attached to the chromophore show very similar Cotton effects. Assignment of transitions for the 2,3-dihydropyrazine chromophore could be made by comparison of the cd and uv spectra.
| Original language | English |
|---|---|
| Pages (from-to) | 783-789 |
| Number of pages | 7 |
| Journal | Heterocycles |
| Volume | 28 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jan 1 1989 |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry
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Hajós, G., & Snatzke, G. (1989). Synthesis and chiroptical properties of 5α-cholest-2-eno[2,3- ]pyrazine derivatives. Heterocycles, 28(2), 783-789. https://doi.org/10.3987/COM-88-S25