Synthesis and application of a fluorous Lawesson's reagent

Convenient chromatography-free product purification

Zoltán Kaleta, G. Tárkányi, A. Gömöry, Ferenc Kálmán, Tamás Nagy, T. Soós

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

A fluorous analogue of Lawesson's reagent for thionation of carbonyl compounds has been developed and its use demonstrated on a series of amides, esters, and ketones. The separation of the Lawesson's reagent-derived byproducts can be achieved by a simple fluorous solid-phase extraction.

Original languageEnglish
Pages (from-to)1093-1095
Number of pages3
JournalOrganic Letters
Volume8
Issue number6
DOIs
Publication statusPublished - Mar 16 2006

Fingerprint

2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide
chromatography
Chromatography
purification
Purification
reagents
Carbonyl compounds
carbonyl compounds
Solid Phase Extraction
synthesis
products
Ketones
Amides
ketones
amides
Byproducts
solid phases
esters
Esters
analogs

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Synthesis and application of a fluorous Lawesson's reagent : Convenient chromatography-free product purification. / Kaleta, Zoltán; Tárkányi, G.; Gömöry, A.; Kálmán, Ferenc; Nagy, Tamás; Soós, T.

In: Organic Letters, Vol. 8, No. 6, 16.03.2006, p. 1093-1095.

Research output: Contribution to journalArticle

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