Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives

Research output: Contribution to journalReview article

39 Citations (Scopus)

Abstract

The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.

Original languageEnglish
Pages (from-to)4828-4842
Number of pages15
JournalCurrent medicinal chemistry
Volume16
Issue number36
DOIs
Publication statusPublished - Dec 18 2009

Keywords

  • Diabetes mellitus
  • Hypertension
  • Kynurenic acid
  • Kynurenic acid derivatives
  • Neurological disorders
  • Retinal damage
  • Schizophrenia

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

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