Syntheses of hydroxylated cyclic β-amino acid derivatives

Márta Palkó, L. Kiss, F. Fülöp

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.

Original languageEnglish
Pages (from-to)3063-3083
Number of pages21
JournalCurrent Medicinal Chemistry
Volume12
Issue number26
DOIs
Publication statusPublished - 2005

Fingerprint

Cyclic Amino Acids
Derivatives
Amino Acids
Research

Keywords

  • β-amino acids
  • Asymmetric synthesis
  • Peptides
  • Selective functionalization

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Pharmacology

Cite this

Syntheses of hydroxylated cyclic β-amino acid derivatives. / Palkó, Márta; Kiss, L.; Fülöp, F.

In: Current Medicinal Chemistry, Vol. 12, No. 26, 2005, p. 3063-3083.

Research output: Contribution to journalArticle

@article{b9cdebcb4e514022b416a8f0caf0a2e9,
title = "Syntheses of hydroxylated cyclic β-amino acid derivatives",
abstract = "This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.",
keywords = "β-amino acids, Asymmetric synthesis, Peptides, Selective functionalization",
author = "M{\'a}rta Palk{\'o} and L. Kiss and F. F{\"u}l{\"o}p",
year = "2005",
doi = "10.2174/092986705774933443",
language = "English",
volume = "12",
pages = "3063--3083",
journal = "Current Medicinal Chemistry",
issn = "0929-8673",
publisher = "Bentham Science Publishers B.V.",
number = "26",

}

TY - JOUR

T1 - Syntheses of hydroxylated cyclic β-amino acid derivatives

AU - Palkó, Márta

AU - Kiss, L.

AU - Fülöp, F.

PY - 2005

Y1 - 2005

N2 - This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.

AB - This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.

KW - β-amino acids

KW - Asymmetric synthesis

KW - Peptides

KW - Selective functionalization

UR - http://www.scopus.com/inward/record.url?scp=28644451440&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=28644451440&partnerID=8YFLogxK

U2 - 10.2174/092986705774933443

DO - 10.2174/092986705774933443

M3 - Article

C2 - 16375701

AN - SCOPUS:28644451440

VL - 12

SP - 3063

EP - 3083

JO - Current Medicinal Chemistry

JF - Current Medicinal Chemistry

SN - 0929-8673

IS - 26

ER -