Synthese of 13-oxa- and 13-thia-PGI2: metabolically stable and biologically potent PGI2 analogues

Lajos Novák, József Aszódi, Csaba Szántay

Research output: Contribution to journalArticle

12 Citations (Scopus)


13-Oxa-13,14-dihydro-PGI2 (6) and 13-thia-13,14-dihydro-PGI2 (9) were synthesized from the corresponding PGF analogues via iodo ether formation and subsequent elimination of HI.

Original languageEnglish
Pages (from-to)2135-2138
Number of pages4
JournalTetrahedron Letters
Issue number20
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthese of 13-oxa- and 13-thia-PGI<sub>2</sub>: metabolically stable and biologically potent PGI<sub>2</sub> analogues'. Together they form a unique fingerprint.

  • Cite this