Synaptic connections of glutamatergic nerve fibres in the rat suprachiasmatic nucleus.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

BACKGROUND AND PURPOSE: The hypothalamic suprachiasmatic nucleus functioning as the principal circadian pacemaker in mammals, has a rich glutamatergic innervation. Nothing is known about the terminations of the glutamatergic fibres. The aim of the present investigations was to study the relationship between glutamatergic axon terminals and vasoactive intestinal polypeptide (VIP), GABA and arginine-vasopressin (AVP) neurons in the cell group. METHODS: Double label immunocytochemistry was used and the brain sections were examined under the electron microscope. Vesicular glutamate transporter type 2 was applied as marker of the glutamatergic elements. Results - Glutamatergic fibers were detected in synaptic contact with GABAergic, VIP- and AVP-positive neurons forming asymmetric type of synapses. CONCLUSION: The findings are the first data on the synaptic contacts of glutamatergic axon terminals with neurochemically identified neurons in the suprachiasmatic nucleus.

Original languageEnglish
Pages (from-to)166-168
Number of pages3
JournalIdeggyógyászati szemle
Volume60
Issue number3-4
Publication statusPublished - Mar 30 2007

Fingerprint

Suprachiasmatic Nucleus
Nerve Fibers
Arginine Vasopressin
Vasoactive Intestinal Peptide
Presynaptic Terminals
Neurons
Vesicular Glutamate Transport Protein 2
Synapses
gamma-Aminobutyric Acid
Mammals
Immunohistochemistry
Electrons
Brain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Synaptic connections of glutamatergic nerve fibres in the rat suprachiasmatic nucleus. / Kiss, J.; Csáki, A.; Csaba, Zsolt; Halász, B.

In: Ideggyógyászati szemle, Vol. 60, No. 3-4, 30.03.2007, p. 166-168.

Research output: Contribution to journalArticle

@article{d6226fe9017c435f8c28b95fdd881ac7,
title = "Synaptic connections of glutamatergic nerve fibres in the rat suprachiasmatic nucleus.",
abstract = "BACKGROUND AND PURPOSE: The hypothalamic suprachiasmatic nucleus functioning as the principal circadian pacemaker in mammals, has a rich glutamatergic innervation. Nothing is known about the terminations of the glutamatergic fibres. The aim of the present investigations was to study the relationship between glutamatergic axon terminals and vasoactive intestinal polypeptide (VIP), GABA and arginine-vasopressin (AVP) neurons in the cell group. METHODS: Double label immunocytochemistry was used and the brain sections were examined under the electron microscope. Vesicular glutamate transporter type 2 was applied as marker of the glutamatergic elements. Results - Glutamatergic fibers were detected in synaptic contact with GABAergic, VIP- and AVP-positive neurons forming asymmetric type of synapses. CONCLUSION: The findings are the first data on the synaptic contacts of glutamatergic axon terminals with neurochemically identified neurons in the suprachiasmatic nucleus.",
author = "J. Kiss and A. Cs{\'a}ki and Zsolt Csaba and B. Hal{\'a}sz",
year = "2007",
month = "3",
day = "30",
language = "English",
volume = "60",
pages = "166--168",
journal = "Ideggyogyaszati Szemle",
issn = "0019-1442",
publisher = "Ifjusagi Lap-es Konyvkiado Vallalat",
number = "3-4",

}

TY - JOUR

T1 - Synaptic connections of glutamatergic nerve fibres in the rat suprachiasmatic nucleus.

AU - Kiss, J.

AU - Csáki, A.

AU - Csaba, Zsolt

AU - Halász, B.

PY - 2007/3/30

Y1 - 2007/3/30

N2 - BACKGROUND AND PURPOSE: The hypothalamic suprachiasmatic nucleus functioning as the principal circadian pacemaker in mammals, has a rich glutamatergic innervation. Nothing is known about the terminations of the glutamatergic fibres. The aim of the present investigations was to study the relationship between glutamatergic axon terminals and vasoactive intestinal polypeptide (VIP), GABA and arginine-vasopressin (AVP) neurons in the cell group. METHODS: Double label immunocytochemistry was used and the brain sections were examined under the electron microscope. Vesicular glutamate transporter type 2 was applied as marker of the glutamatergic elements. Results - Glutamatergic fibers were detected in synaptic contact with GABAergic, VIP- and AVP-positive neurons forming asymmetric type of synapses. CONCLUSION: The findings are the first data on the synaptic contacts of glutamatergic axon terminals with neurochemically identified neurons in the suprachiasmatic nucleus.

AB - BACKGROUND AND PURPOSE: The hypothalamic suprachiasmatic nucleus functioning as the principal circadian pacemaker in mammals, has a rich glutamatergic innervation. Nothing is known about the terminations of the glutamatergic fibres. The aim of the present investigations was to study the relationship between glutamatergic axon terminals and vasoactive intestinal polypeptide (VIP), GABA and arginine-vasopressin (AVP) neurons in the cell group. METHODS: Double label immunocytochemistry was used and the brain sections were examined under the electron microscope. Vesicular glutamate transporter type 2 was applied as marker of the glutamatergic elements. Results - Glutamatergic fibers were detected in synaptic contact with GABAergic, VIP- and AVP-positive neurons forming asymmetric type of synapses. CONCLUSION: The findings are the first data on the synaptic contacts of glutamatergic axon terminals with neurochemically identified neurons in the suprachiasmatic nucleus.

UR - http://www.scopus.com/inward/record.url?scp=34347216021&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34347216021&partnerID=8YFLogxK

M3 - Article

C2 - 17451061

AN - SCOPUS:34347216021

VL - 60

SP - 166

EP - 168

JO - Ideggyogyaszati Szemle

JF - Ideggyogyaszati Szemle

SN - 0019-1442

IS - 3-4

ER -