Surveillance and management of patients with tuberous sclerosis complex

A. Fogarasi, Zsuzsanna Gyorsok, Ti'mea Bodó

Research output: Contribution to journalArticle

Abstract

Tuberous sclerosis complex (TSC) is an autosomal dominant disease due to the uncontrolled differentiation, proliferation, and migration of cells in several organs. Clinical expression is highly variable, from mild skin findings and asymptomatic brain lesions to seizures, mental retardation, autism, and potentially fatal kidney, cardiac, or pulmonary disease. Aim of this paper is to summarize the diagnostic criteria, surveillance and therapeutic issues of this multisystemic disorder emphasizing the most important neurological consequences. Presenting the state-of-The-Art management recommendations and comparing them with the local protocols, we hope that our review might help in the proper assessment of one of the most important single gene disorder.

Original languageEnglish
Pages (from-to)97-103
Number of pages7
JournalIdeggyogyaszati Szemle
Volume70
Issue number3-4
DOIs
Publication statusPublished - Mar 30 2017

Keywords

  • Manogement guidelines
  • Surveillance
  • Therapy
  • Tuberous sclerosis complex

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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