A colorectalis tumorok tüdô metastasisainak sebészi kezelése.

Translated title of the contribution: Surgical treatment of pulmonary metastases of colorectal cancers

István Zapf, F. Tamás Molnár, István Benko, Nagy Károly Kalmar, Zalán Szántó, László Pótó, O. Horvath

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Abstract

INTRODUCTION: Results of a retrospective study of patients who underwent pulmonary metastasectomies after colorectal surgery in the last five years are reported here. Prognostic factors are evaluated and analyzed in the context of current literature. MATERIAL AND METHODS: 37 lung resections were performed in 33 patients between 2001 and 2006, the male:female ratio was 19:14. The average age was 61.3 years (49-76). We analyzed the extent of lung resections, disease free intervals (DFI), laterality of the tumours, number and locations of metastases, lymph node involvements and the incidence of resection of hepatic metastases. Altogether, 20 solitary lung metastases were removed and 17 multiple resections were performed. 25 sublobar resections, 11 lobectomies and one pneumonectomy were carried out. 18 patients had right sided, eight patients had left sided and six patients had bilateral disease. 6 of the 33 patients underwent either synchronous or metachronous liver resection for hepatic metastases. RESULTS: Survivals were calculated by the Kaplan-Meier method. The average DFI was 27.6 months. When all patients were considered, the average survival was 28 months. 52% of the patients had a 3-year postoperative survival, if lung metastases were present only. CONCLUSIONS: Patients benefit from surgical removal of lung metastases of colorectal cancer. There were no differences in survival rates between patients who underwent resection of solitary or multiple lung metastases up to seven deposits. However, the average survival was 12 months shorter if hilar/mediastinal lymph nodes were involved. Furthermore, the average survival of six patients with hepatic metastases was 10 months shorter than the rest of the group. There was no benefit of DFI over 24 months. None of the other prognostic factors showed significant difference.

Original languageHungarian
Pages (from-to)130-135
Number of pages6
JournalMagyar sebészet
Volume60
Issue number3
DOIs
Publication statusPublished - May 2007

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Colorectal Neoplasms
Neoplasm Metastasis
Lung
Survival
Therapeutics
Liver
Lymph Nodes
Metastasectomy
Colorectal Surgery
Pneumonectomy
Patient Rights
Lung Diseases
Survival Rate
Retrospective Studies
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Zapf, I., Molnár, F. T., Benko, I., Kalmar, N. K., Szántó, Z., Pótó, L., & Horvath, O. (2007). A colorectalis tumorok tüdô metastasisainak sebészi kezelése. Magyar sebészet, 60(3), 130-135. https://doi.org/10.1556/MaSeb.60.2007.3.2

A colorectalis tumorok tüdô metastasisainak sebészi kezelése. / Zapf, István; Molnár, F. Tamás; Benko, István; Kalmar, Nagy Károly; Szántó, Zalán; Pótó, László; Horvath, O.

In: Magyar sebészet, Vol. 60, No. 3, 05.2007, p. 130-135.

Research output: Contribution to journalArticle

Zapf, I, Molnár, FT, Benko, I, Kalmar, NK, Szántó, Z, Pótó, L & Horvath, O 2007, 'A colorectalis tumorok tüdô metastasisainak sebészi kezelése.', Magyar sebészet, vol. 60, no. 3, pp. 130-135. https://doi.org/10.1556/MaSeb.60.2007.3.2
Zapf I, Molnár FT, Benko I, Kalmar NK, Szántó Z, Pótó L et al. A colorectalis tumorok tüdô metastasisainak sebészi kezelése. Magyar sebészet. 2007 May;60(3):130-135. https://doi.org/10.1556/MaSeb.60.2007.3.2
Zapf, István ; Molnár, F. Tamás ; Benko, István ; Kalmar, Nagy Károly ; Szántó, Zalán ; Pótó, László ; Horvath, O. / A colorectalis tumorok tüdô metastasisainak sebészi kezelése. In: Magyar sebészet. 2007 ; Vol. 60, No. 3. pp. 130-135.
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N2 - INTRODUCTION: Results of a retrospective study of patients who underwent pulmonary metastasectomies after colorectal surgery in the last five years are reported here. Prognostic factors are evaluated and analyzed in the context of current literature. MATERIAL AND METHODS: 37 lung resections were performed in 33 patients between 2001 and 2006, the male:female ratio was 19:14. The average age was 61.3 years (49-76). We analyzed the extent of lung resections, disease free intervals (DFI), laterality of the tumours, number and locations of metastases, lymph node involvements and the incidence of resection of hepatic metastases. Altogether, 20 solitary lung metastases were removed and 17 multiple resections were performed. 25 sublobar resections, 11 lobectomies and one pneumonectomy were carried out. 18 patients had right sided, eight patients had left sided and six patients had bilateral disease. 6 of the 33 patients underwent either synchronous or metachronous liver resection for hepatic metastases. RESULTS: Survivals were calculated by the Kaplan-Meier method. The average DFI was 27.6 months. When all patients were considered, the average survival was 28 months. 52% of the patients had a 3-year postoperative survival, if lung metastases were present only. CONCLUSIONS: Patients benefit from surgical removal of lung metastases of colorectal cancer. There were no differences in survival rates between patients who underwent resection of solitary or multiple lung metastases up to seven deposits. However, the average survival was 12 months shorter if hilar/mediastinal lymph nodes were involved. Furthermore, the average survival of six patients with hepatic metastases was 10 months shorter than the rest of the group. There was no benefit of DFI over 24 months. None of the other prognostic factors showed significant difference.

AB - INTRODUCTION: Results of a retrospective study of patients who underwent pulmonary metastasectomies after colorectal surgery in the last five years are reported here. Prognostic factors are evaluated and analyzed in the context of current literature. MATERIAL AND METHODS: 37 lung resections were performed in 33 patients between 2001 and 2006, the male:female ratio was 19:14. The average age was 61.3 years (49-76). We analyzed the extent of lung resections, disease free intervals (DFI), laterality of the tumours, number and locations of metastases, lymph node involvements and the incidence of resection of hepatic metastases. Altogether, 20 solitary lung metastases were removed and 17 multiple resections were performed. 25 sublobar resections, 11 lobectomies and one pneumonectomy were carried out. 18 patients had right sided, eight patients had left sided and six patients had bilateral disease. 6 of the 33 patients underwent either synchronous or metachronous liver resection for hepatic metastases. RESULTS: Survivals were calculated by the Kaplan-Meier method. The average DFI was 27.6 months. When all patients were considered, the average survival was 28 months. 52% of the patients had a 3-year postoperative survival, if lung metastases were present only. CONCLUSIONS: Patients benefit from surgical removal of lung metastases of colorectal cancer. There were no differences in survival rates between patients who underwent resection of solitary or multiple lung metastases up to seven deposits. However, the average survival was 12 months shorter if hilar/mediastinal lymph nodes were involved. Furthermore, the average survival of six patients with hepatic metastases was 10 months shorter than the rest of the group. There was no benefit of DFI over 24 months. None of the other prognostic factors showed significant difference.

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