Surgical aspects of Intraductal papillary mucinous neoplasms of the pancreas

A. Oláh, D. Kollár

Research output: Contribution to journalArticle

Abstract

Intraductal papillary mucinous neoplasms (IPMN) play an important role amongst exocrine tumours of the pancreas due to several causes. Although they count for only 1% of all the tumours, they represent some 20-30% of all cystic neoplasms, a histologically defined group that has gained a lot of attention lately. IPMNs of the main or the secondary (branch) pancreatic ducts have remarkably different rates of malignant transformation, prognosis and thus indication for surgery. Prognosis of a ductal carcinoma developing from IPMN does not differ from 'classic' ductal adenocarcinoma, with a very poor (10%) 5-year survival rate. However, prognosis of IPMN can still be regarded favourable, because the above rate can be as high as 70% if the tumour is non-invasive. This fact leads to the importance of diagnosing and resecting IPMN before its malignant transformation into an invasive carcinoma.

Original languageEnglish
Pages (from-to)413-417
Number of pages5
JournalChirurgia (Romania)
Volume110
Issue number5
Publication statusPublished - Sep 1 2015

Fingerprint

Pancreatic Neoplasms
Neoplasms
Exocrine Pancreas
Ductal Carcinoma
Pancreatic Ducts
Adenocarcinoma
Carcinoma

Keywords

  • Intraductal papillary mucinous neoplasm
  • Pancreas

ASJC Scopus subject areas

  • Surgery

Cite this

Surgical aspects of Intraductal papillary mucinous neoplasms of the pancreas. / Oláh, A.; Kollár, D.

In: Chirurgia (Romania), Vol. 110, No. 5, 01.09.2015, p. 413-417.

Research output: Contribution to journalArticle

@article{1dc791086f264368bc6674d5bf05561e,
title = "Surgical aspects of Intraductal papillary mucinous neoplasms of the pancreas",
abstract = "Intraductal papillary mucinous neoplasms (IPMN) play an important role amongst exocrine tumours of the pancreas due to several causes. Although they count for only 1{\%} of all the tumours, they represent some 20-30{\%} of all cystic neoplasms, a histologically defined group that has gained a lot of attention lately. IPMNs of the main or the secondary (branch) pancreatic ducts have remarkably different rates of malignant transformation, prognosis and thus indication for surgery. Prognosis of a ductal carcinoma developing from IPMN does not differ from 'classic' ductal adenocarcinoma, with a very poor (10{\%}) 5-year survival rate. However, prognosis of IPMN can still be regarded favourable, because the above rate can be as high as 70{\%} if the tumour is non-invasive. This fact leads to the importance of diagnosing and resecting IPMN before its malignant transformation into an invasive carcinoma.",
keywords = "Intraductal papillary mucinous neoplasm, Pancreas",
author = "A. Ol{\'a}h and D. Koll{\'a}r",
year = "2015",
month = "9",
day = "1",
language = "English",
volume = "110",
pages = "413--417",
journal = "Chirurgia (Bucharest, Romania : 1990)",
issn = "1221-9118",
publisher = "Editura Medicala",
number = "5",

}

TY - JOUR

T1 - Surgical aspects of Intraductal papillary mucinous neoplasms of the pancreas

AU - Oláh, A.

AU - Kollár, D.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Intraductal papillary mucinous neoplasms (IPMN) play an important role amongst exocrine tumours of the pancreas due to several causes. Although they count for only 1% of all the tumours, they represent some 20-30% of all cystic neoplasms, a histologically defined group that has gained a lot of attention lately. IPMNs of the main or the secondary (branch) pancreatic ducts have remarkably different rates of malignant transformation, prognosis and thus indication for surgery. Prognosis of a ductal carcinoma developing from IPMN does not differ from 'classic' ductal adenocarcinoma, with a very poor (10%) 5-year survival rate. However, prognosis of IPMN can still be regarded favourable, because the above rate can be as high as 70% if the tumour is non-invasive. This fact leads to the importance of diagnosing and resecting IPMN before its malignant transformation into an invasive carcinoma.

AB - Intraductal papillary mucinous neoplasms (IPMN) play an important role amongst exocrine tumours of the pancreas due to several causes. Although they count for only 1% of all the tumours, they represent some 20-30% of all cystic neoplasms, a histologically defined group that has gained a lot of attention lately. IPMNs of the main or the secondary (branch) pancreatic ducts have remarkably different rates of malignant transformation, prognosis and thus indication for surgery. Prognosis of a ductal carcinoma developing from IPMN does not differ from 'classic' ductal adenocarcinoma, with a very poor (10%) 5-year survival rate. However, prognosis of IPMN can still be regarded favourable, because the above rate can be as high as 70% if the tumour is non-invasive. This fact leads to the importance of diagnosing and resecting IPMN before its malignant transformation into an invasive carcinoma.

KW - Intraductal papillary mucinous neoplasm

KW - Pancreas

UR - http://www.scopus.com/inward/record.url?scp=84954472534&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954472534&partnerID=8YFLogxK

M3 - Article

C2 - 26531783

AN - SCOPUS:84954472534

VL - 110

SP - 413

EP - 417

JO - Chirurgia (Bucharest, Romania : 1990)

JF - Chirurgia (Bucharest, Romania : 1990)

SN - 1221-9118

IS - 5

ER -