119Sn Mössbauer study of Sn-containing radiopharmaceutical kits

E. Kuzmann, Z. Homonnay, Sz Keresztes, M. Antalffy, J. Környei

Research output: Contribution to journalArticle


Sn-containing radiopharmaceutical kits, MULTIBONE (composed from stannous chloride dihydrate and EDTMP (ethylene-diamine-tetramethylene phosphonate) and PHYTON (composed from stannous chloride dihydrate and PHYTATE (myo-inositol-hexaphosphate ester) kits, to be used for monitoring in liver tumor therapy, were characterized by 119Sn Mössbauer spectroscopy and XRD measurements. XRD revealed the amorphous nature of the Sn-containing compounds. 80 K 119Sn Mössbauer spectra of both compounds indicated the dominant presence of tin(II) state with characteristic Mössbauer parameters of δ = 3.12 ± 0.01 mms−1 and Δ = 1.84 ± 0.02 mms−1 as well as δ = 3.01 ± 0.01 ± 0.01 mms−1 and Δ = 1.73 ± 0.02 mms−1 for Sn-PHYTATE and Sn-EDTMP, respectively. The occurrence of tin(IV) in Sn-MULTIBONE was as low as measured in the precursor stannous chloride dihydrate (∼3%).

Original languageEnglish
Article number32
JournalHyperfine Interactions
Issue number1
Publication statusPublished - Dec 1 2018


  • Sn Mössbauer spectroscopy
  • Occurrence of tin(II)
  • Pharmaceutical kits
  • Sn-Multibone
  • Sn-Phytate
  • Stability

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Nuclear and High Energy Physics
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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