Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas

Dániel Cs Simkó, Péter Elekes, Vivien Pázmándi, Z. Novák

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A novel method for the ortho alkylation of acetanilide and aromatic urea derivatives via C-H activation was developed. Alkyl dibenzothiophenium salts are considered to be new reagents for the palladium-catalyzed C-H activation reaction, which enables the transfer of methyl and other alkyl groups from the sulfonium salt to the aniline derivatives under mild catalytic conditions.

Original languageEnglish
Pages (from-to)676-679
Number of pages4
JournalOrganic Letters
Volume20
Issue number3
DOIs
Publication statusPublished - Feb 2 2018

Fingerprint

Anilides
Alkylating Agents
alkylation
Alkylation
Palladium
ureas
Urea
palladium
Salts
Chemical activation
acetanilide
activation
salts
Derivatives
aniline
reagents

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas. / Simkó, Dániel Cs; Elekes, Péter; Pázmándi, Vivien; Novák, Z.

In: Organic Letters, Vol. 20, No. 3, 02.02.2018, p. 676-679.

Research output: Contribution to journalArticle

Simkó, Dániel Cs ; Elekes, Péter ; Pázmándi, Vivien ; Novák, Z. / Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas. In: Organic Letters. 2018 ; Vol. 20, No. 3. pp. 676-679.
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