Sudden cardiac death from parvovirus B19 myocarditis in a young man with Brugada syndrome

Zoltan Juhasz, L. Tiszlavicz, Beatrix Kele, Gabriella Terhes, Judit Deak, L. Rudas, Eva Kereszty

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cardiovascular diseases are the leading cause of sudden death all over the world. The aetiology of sudden cardiac death among young adults includes Brugada syndrome and myocarditis. Brugada syndrome is a genetic abnormality of sodium channels in the myocardium with a characteristic electrocardiographic pattern. Myocarditis has several aetiologies including infections. One of the most common cardiotropic viruses is parvovirus B19. This infection presents as a febrile illness in childhood and may result in fatal outcome, more frequently in adults. In this report we present a case of a young man who suffered from a mild upper respiratory tract infection. After recovery he had an episode of syncope and was diagnosed with Brugada syndrome. Some weeks later he died suddenly at home while sleeping. The detailed forensic pathological, histological and microbiological investigation revealed a parvovirus B19-associated myocarditis. Synergic effect of structural and functional abnormalities of the myocardium may lead to death. The cause and potential complications (eg. myocarditis) of even mild infections should be monitored carefully.

Original languageEnglish
Pages (from-to)8-13
Number of pages6
JournalJournal of Forensic and Legal Medicine
Volume25
DOIs
Publication statusPublished - 2014

Fingerprint

Brugada Syndrome
Parvovirus
Sudden Cardiac Death
Myocarditis
death
etiology
cause of death
young adult
Myocardium
illness
Infection
childhood
Disease
Fatal Outcome
cause
Sodium Channels
Syncope
Sudden Death
Respiratory Tract Infections
Young Adult

Keywords

  • Brugada syndrome
  • Myocarditis
  • Parvovirus
  • Sudden death

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Law
  • Medicine(all)

Cite this

Sudden cardiac death from parvovirus B19 myocarditis in a young man with Brugada syndrome. / Juhasz, Zoltan; Tiszlavicz, L.; Kele, Beatrix; Terhes, Gabriella; Deak, Judit; Rudas, L.; Kereszty, Eva.

In: Journal of Forensic and Legal Medicine, Vol. 25, 2014, p. 8-13.

Research output: Contribution to journalArticle

Juhasz, Zoltan ; Tiszlavicz, L. ; Kele, Beatrix ; Terhes, Gabriella ; Deak, Judit ; Rudas, L. ; Kereszty, Eva. / Sudden cardiac death from parvovirus B19 myocarditis in a young man with Brugada syndrome. In: Journal of Forensic and Legal Medicine. 2014 ; Vol. 25. pp. 8-13.
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