Successful treatment of a T1 cancer of the pancreatic head with high dose rate brachytherapy and external radiotherapy

Zoltán Takácsi-Nagy, János Varga, Imre Poller, János Fodor, Csaba Polgár, Ágota Petrányi, Tibor Major, György Németh

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In this report, a unique case of a localized (T1N0M0) adenocarcinoma of the head of the pancreas is presented, which was successfully treated with interstitial high dose rate brachytherapy combined with percutan irradiation after biopsy. A total dose of 18 Gy was delivered with brachytherapy (6 Gy per fraction on three consecutive days) to the tumor via after-loading catheter. Brachytherapy was followed by external radiotherapy, delivering an additional dose of 46 Gy (18 MV-x) with four-field technique using conventional fractionation (2 Gy/day). Thirty-six months after completion of the treatment the patient is alive with no evidence of disease. The combinatidn of interstitial high dose rate brachytherapy and external beam radiation therapy may be an effective tool to deliver curative dose without any significant sequelae in the treatment of operable pancreatic carcinoma, when the patient's condition contraindicates surgery.

Original languageEnglish
Pages (from-to)844-846
Number of pages3
JournalHepato-Gastroenterology
Volume49
Issue number45
Publication statusPublished - Jan 1 2002

Keywords

  • After-loading brachytherapy
  • High dose rate
  • Pancreatic cancer

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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