Hepatitis C-vírus sikeres eliminálása hepatocellularis carcinoma miatti lobectomiát követoen

Translated title of the contribution: Successful clearing of hepatitis C virus, after liver lobectomy in a patient with hepatocellular, carcinoma

Alexandra Wimmer, J. Fehér, G. Lengyel

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Hepatocellular carcinoma develops frequently subsequently upon chronic hepatitis C and B virus infections. Hepatitis B virus has a direct, while hepatitis C virus an indirect role in hepatocarcinogenesis. The aim of our work: To demostrate a very unique and interesting case where after the elimination of early detected duplex hepatocellular carcinoma with a combined therapy of PEG-interferon and ribavirin, hepatitis C virus could be eliminated. Case presentation: A 53-year-old male patient had chronic hepatitis C infection in his anamnesis. In 1995 histological examination confirmed cirrhosis in his liver. One year later be was non-responder for conventional interferon therapy. In 2002 CT examination confirmed a process with multiple plexus in the liver. With cytologycal proof of hepatocellular carcinoma, a resection of the tumor by left-lobectomy of the liver was carried out. Four years after the operation a one-year PEG-interferon-alfa-2a and ribavirin combined therapy had been applied. The patient became virologically negative. Conclusion: In chronic liver diseases carcinoma can develop from multiple center at the same time. PEG-interferon and ribavirin combined therapy can be effective in chronic liver disease as well as after resection of estabilished hepatocellular carcinoma.

Original languageHungarian
Pages (from-to)2143-2146
Number of pages4
JournalOrvosi Hetilap
Volume149
Issue number45
DOIs
Publication statusPublished - Nov 9 2008

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Hepacivirus
Ribavirin
Hepatocellular Carcinoma
Interferons
Liver
Chronic Hepatitis C
Hepatitis B virus
Liver Diseases
Chronic Disease
Chronic Hepatitis B
Virus Diseases
Therapeutics
Liver Cirrhosis
Carcinoma
Infection
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hepatitis C-vírus sikeres eliminálása hepatocellularis carcinoma miatti lobectomiát követoen. / Wimmer, Alexandra; Fehér, J.; Lengyel, G.

In: Orvosi Hetilap, Vol. 149, No. 45, 09.11.2008, p. 2143-2146.

Research output: Contribution to journalArticle

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