Abstract
The sensing ability of three 1,10-diaza-18-crown-6 based sensors bearing a coumarin fluorophore was studied and compared with the analogous monoaza-18-crown-6 sensor. Coordination experiments between hosts and organic ammonium salts with varying steric demand were studied using fluorescence and 1H NMR spectroscopy. We have found that the fluorescent signal generated on complexation was greatly influenced by the structure of the sensor. Surprisingly, in two cases, we observed the decrease of fluorescence on complexation, which was attributed to changes in the conformational dynamics of the sensors on complexation.
| Original language | English |
|---|---|
| Pages (from-to) | 6191-6195 |
| Number of pages | 5 |
| Journal | Tetrahedron |
| Volume | 64 |
| Issue number | 27 |
| DOIs | |
| Publication status | Published - Jun 30 2008 |
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ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Substituent dependent fluorescence response of diazacrown-based PET sensors. / Nagy, K.; Béni, S.; Szakács, Zoltán; Bényei, A.; Noszál, B.; Kele, P.; Kotschy, András.
In: Tetrahedron, Vol. 64, No. 27, 30.06.2008, p. 6191-6195.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Substituent dependent fluorescence response of diazacrown-based PET sensors
AU - Nagy, K.
AU - Béni, S.
AU - Szakács, Zoltán
AU - Bényei, A.
AU - Noszál, B.
AU - Kele, P.
AU - Kotschy, András
PY - 2008/6/30
Y1 - 2008/6/30
N2 - The sensing ability of three 1,10-diaza-18-crown-6 based sensors bearing a coumarin fluorophore was studied and compared with the analogous monoaza-18-crown-6 sensor. Coordination experiments between hosts and organic ammonium salts with varying steric demand were studied using fluorescence and 1H NMR spectroscopy. We have found that the fluorescent signal generated on complexation was greatly influenced by the structure of the sensor. Surprisingly, in two cases, we observed the decrease of fluorescence on complexation, which was attributed to changes in the conformational dynamics of the sensors on complexation.
AB - The sensing ability of three 1,10-diaza-18-crown-6 based sensors bearing a coumarin fluorophore was studied and compared with the analogous monoaza-18-crown-6 sensor. Coordination experiments between hosts and organic ammonium salts with varying steric demand were studied using fluorescence and 1H NMR spectroscopy. We have found that the fluorescent signal generated on complexation was greatly influenced by the structure of the sensor. Surprisingly, in two cases, we observed the decrease of fluorescence on complexation, which was attributed to changes in the conformational dynamics of the sensors on complexation.
UR - http://www.scopus.com/inward/record.url?scp=44349100931&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44349100931&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2008.05.006
DO - 10.1016/j.tet.2008.05.006
M3 - Article
AN - SCOPUS:44349100931
VL - 64
SP - 6191
EP - 6195
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 27
ER -