Substituent and solvent dependent conformations of some saturated diazatricyclic compounds

Barbara Balázs, Péter Nemes, Pál Scheiber, Gábor Tóth

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The double Mannich condensation of 2-quinolizidone with formaldehyde and methyl amine resulted in the 11-methyl-7,11- diazatricyclo[7.3.1.02,7]tridecan-13-one of endo-type selectively. The stereochemistry, isomerism and conformational behaviour of derivatives obtained by reduction at C-13 were investigated extensively by one- and two- dimensional 1H, 13C and 15N NMR spectroscopy. The site of the protonation and its effect on the conformational equilibria and chemical shifts were also revealed.

Original languageEnglish
Pages (from-to)153-160
Number of pages8
JournalJournal of Molecular Structure
Volume475
Issue number2-3
DOIs
Publication statusPublished - Feb 2 1999

Keywords

  • C and N NMR spectroscopy
  • Conformation
  • H
  • Protonation effect
  • Saturated diazatricycles
  • Stereochemistry

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Organic Chemistry
  • Inorganic Chemistry

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