Subset specificity of lupus antilymphocyte antibodies studied by two-colour microfluorimetry

Péter Surányi, László Mátyus, Ildikó Sonkoly, Gyula Szegedi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Subset specific lymphocytotoxic activity of lupus sera was studied by a combination of selective immunofluorescence labelling and complement-mediated lysis. Most frequently death of B cells was detected. Many of the sera caused lysis of T lymphocytes; selective cytotoxicity against suppressor T cells could be observed less frequently. All the anti-T4, anti-T8 and anti-B lymphocyte antibodies proved to be cold reactive.

Original languageEnglish
Pages (from-to)91-93
Number of pages3
JournalImmunology letters
Volume10
Issue number2
DOIs
Publication statusPublished - 1985

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Keywords

  • antilymphocyte antibodies
  • lymphocyte subsets
  • systemic lupus erythematosus
  • two-colour microfluorimetry

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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