Subcellular distribution of neurotransmitter receptors and voltage-gated ion channels

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter describes the subcellular distribution of glutamate and GABA receptors and voltage-activated channels on the neuronal surface, as detected with a variety of light and electron-microscopic techniques. Ionotropic glutamate and GABAA receptors are concentrated at glutamatergic and GABAergic synapses, respectively, on the somatodendritic domains of nerve cells. Different AMPA receptor subtypes are selectively targeted to functionally distinct glutamatergic synapses of a single cell. Furthermore, synaptic AMPA receptor number and density are also highly regulated at a single cell level.

Original languageEnglish
Title of host publicationDendrites
PublisherOxford University Press
ISBN (Print)9780191724206, 9780198566564
DOIs
Publication statusPublished - Mar 22 2012

Fingerprint

Neurotransmitter Receptor
AMPA Receptors
Ion Channels
Synapses
Ionotropic Glutamate Receptors
GABA Receptors
Glutamate Receptors
GABA-A Receptors
Electrons
Neurons
Light

Keywords

  • GABA receptors
  • Glutamate
  • Nerve cells
  • Somatodendritic domains
  • Subcellular distribution
  • Voltage-activated channels

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Subcellular distribution of neurotransmitter receptors and voltage-gated ion channels. / Nusser, Z.

Dendrites. Oxford University Press, 2012.

Research output: Chapter in Book/Report/Conference proceedingChapter

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