1H and 13C NMR investigation of 20-hydroxyecdysone dioxolane derivatives, a novel group of MDR modulator agents

Attila Balázs, Attila Hunyadi, Jõzsef Csábi, Nikoletta Jedlinszki, Ana Martins, András Simon, Gábor Tõth

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12 Citations (Scopus)

Abstract

The synthesis, structure elucidation and the complete 1H and 13C signal assignment of a series of dioxolane derivatives of 20-hydroxyecdysone, synthesized as novel modulators of multidrug resistance, are presented. The structures and NMR signal assignment were established by comprehensive one-dimensional and two-dimensional NMR spectroscopy supported by mass spectrometry.

Original languageEnglish
Pages (from-to)830-836
Number of pages7
JournalMagnetic Resonance in Chemistry
Volume51
Issue number12
DOIs
Publication statusPublished - Dec 1 2013

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Keywords

  • 20-hydroxyecdysone dioxolanes
  • C NMR
  • H NMR
  • P-glycoprotein
  • antitumor agents
  • stereochemistry

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)

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