Sub-exponential growth and coexistence of non-enzymatically replicating templates

Eörs Szathmáry, Irina Gladkih

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Abstract

The experimentally reported kinetic behaviour (sub-exponential but supra-linear growth) of non-enzymatic template replication is incorporated into a simple model of template competition. Sub-exponential growth is shown to lead to coexistence invariably. Thus coexistence of different non-enzymatically replicating sequences is predicted. This type of coexistence could have been important in maintaining a sufficient diversity of RNA modules used later to build functional molecules such as ribozymes. Experimental tests of this theoretical prediction are possible.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalJournal of Theoretical Biology
Volume138
Issue number1
DOIs
Publication statusPublished - May 7 1989

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ASJC Scopus subject areas

  • Statistics and Probability
  • Modelling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics

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