Study of the structure of coherent emulsions

István Eros, Magdolna Kónya, Ildikó Csóka

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9 Citations (Scopus)

Abstract

The object of the study was to analyse relationship between the rheological properties, thermogravimetric behaviour, physical stability, and the wetting contact angle of the lipophilic and aqueous phase of 300 creams of different compositions with a high water content (60-80%, w/w). The starting point was Junginger's theory: water is found in the cream structure in energetic (interlamellar) and steric forms (bulk water). Based on our investigations, an exponential function was found to exist between the contact angle of wetting and the slope of the TG-curves, between the contact angle of wetting and the viscosity of the creams, and between the contact angle of wetting and the evaporation rate of water. A linear relationship was found between the contact angle of wetting and the quantity of water separable by centrifugation.

Original languageEnglish
Pages (from-to)75-84
Number of pages10
JournalInternational Journal of Pharmaceutics
Volume256
Issue number1-2
DOIs
Publication statusPublished - Apr 30 2003

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Keywords

  • Contact angle
  • Cream structure
  • Evaporation of water
  • Rheology
  • Thermal analysis

ASJC Scopus subject areas

  • Pharmaceutical Science

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