ETUDE DE LA REACTIVITE DES TUMEURS A CELLULES GEANTES DES OS A DIFFERENTES LECTINES

Translated title of the contribution: Study of the reactivity of giant cell bone tumours to various lectins

T. Illes, J. Dubousset, M. Szendroi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The authors have examined 18 cases of giant cell bone tumours using various lectins. Type I stromal cells resembling fibroblasts and participating in the construction of matrix were Con A positive. The intensity of Con A binding and the number of positive cells increased with increasing stage. The nature and intensity of PNA-lectin binding in giant cells, after digestion with neuraminidase, varied according to the stage. While in Group I giant cells, 30% of cells were negative and, in the great majority of cells, the reaction was limited to a clearly defined segment of the membrane, in Group III tumours, the proportion of negative cells was approximately 1% and a diffuse and very intense intracytoplasmic reaction was observed in 60% of the positive cells. According to the authors, the histochemical study of lectins could help classify giant cell tumours.

Translated title of the contributionStudy of the reactivity of giant cell bone tumours to various lectins
Original languageFrench
Pages (from-to)331-337
Number of pages7
JournalArchives d'Anatomie et de Cytologie Pathologiques
Volume43
Issue number5-6
Publication statusPublished - Dec 1 1995

Keywords

  • Bone tumours
  • Giant cell bone tumours
  • Lectins

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

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