Study of the melanin in paraffin embedded specimens of ocular melanoma by electron spin resonance (ESP)

Research output: Contribution to journalArticle

Abstract

The Electron Spin Resonance (ESP) spectrum of ocular melanomas embedded in paraffin was studied. In the g~2.003 range of the spectrum a mark of a free radical was detected. The correlation between the amplitude of the latter and the number of melanin granules in sections was studied. Considering the positive correlation revealed, the authors believe that ESR spectroscopy is a suitable tool for detecting melanin in paraffin embedded specimens. As an effect of oxidation or reduction melanin turns pale; however this phenomenon is not in close connection with the decrease of the amplitude of the free-radical-mark. Very seldomly different types of spectrum (peroxide, cupri-ion) may appear, so it is reasonable to study large numbers of specimens.

Original languageEnglish
Pages (from-to)219-224
Number of pages6
JournalMorphologiai es Igazsagugyi Orvosi Szemle
Volume20
Issue number3
Publication statusPublished - Jan 1 1980

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Study of the melanin in paraffin embedded specimens of ocular melanoma by electron spin resonance (ESP)'. Together they form a unique fingerprint.

  • Cite this