The Electron Spin Resonance (ESP) spectrum of ocular melanomas embedded in paraffin was studied. In the g~2.003 range of the spectrum a mark of a free radical was detected. The correlation between the amplitude of the latter and the number of melanin granules in sections was studied. Considering the positive correlation revealed, the authors believe that ESR spectroscopy is a suitable tool for detecting melanin in paraffin embedded specimens. As an effect of oxidation or reduction melanin turns pale; however this phenomenon is not in close connection with the decrease of the amplitude of the free-radical-mark. Very seldomly different types of spectrum (peroxide, cupri-ion) may appear, so it is reasonable to study large numbers of specimens.
|Number of pages||6|
|Journal||Morphologiai es Igazsagugyi Orvosi Szemle|
|Publication status||Published - Jan 1 1980|
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