During the optical resolution of racemic N-methylamphetamine by half an equivalent of R,R-tartaric acid in the presence of half an equivalent of hydrochloric acid the tartrate salt of the R-base precipitates with a low optical purity. The optical purity of the precipitated salt is increased by enantiomer exchange between the solid and solvent phase.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry