A familiáris thrombophilia leggyakoribb okának, a Leiden mutációnak (faktor V. Q506) vizsgálata 116 thrombosisos betegben.

Translated title of the contribution: Study of the Leiden mutation (factor VQ 506), the most frequent cause of thrombophilia, in 116 thrombosis patients

A. Nagy, B. Melegh, H. Losonczy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The incidence of Leiden mutation was examined by PCR method in 116 thrombophilic patients in random fashion. Mean age at the first thrombotic episode was 30.97 years. 90 patients had positive family history for thrombosis, 67 had more than one thrombotic episodes. APC resistance with laboratory test was found in 51 cases (44%). F V Leiden mutation was proven in 44 patients (38%). 10 being homozygous and 34 heterozygous out of them.

Original languageHungarian
Pages (from-to)2797-2800
Number of pages4
JournalOrvosi Hetilap
Volume138
Issue number44
Publication statusPublished - Nov 2 1997

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Thrombophilia
Thrombosis
Mutation
Activated Protein C Resistance
Polymerase Chain Reaction
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A familiáris thrombophilia leggyakoribb okának, a Leiden mutációnak (faktor V. Q506) vizsgálata 116 thrombosisos betegben. / Nagy, A.; Melegh, B.; Losonczy, H.

In: Orvosi Hetilap, Vol. 138, No. 44, 02.11.1997, p. 2797-2800.

Research output: Contribution to journalArticle

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