Study of solvent adsorption on chemically bonded stationary phases by microcalorimetry and liquid chromatography

Bogusław Buszewski, Szymon Bocian, Gerhard Rychlicki, Péter Vajda, A. Felinger

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A detailed, molecular-level description of the sorption mechanism in reversed-phase liquid chromatography is of great interest to analytical chemists. For this purpose, solvent adsorption in the octadecyl stationary bonded phase was investigated. Preferential adsorption of solvents from an acetonitrile-water and methanol-water mobile phase was measured on a series of non-end-capped octadecyl bonded phases with different coverage densities of bonded ligands using the minor disturbance method. For a comparison, a microcalorimetric study of organic solvent adsorption on the stationary phase was executed. The results from the excess isotherm measurement agree well with the experimental measurement of the heat of immersion of the bonded stationary phases by the test solvents. The microcalorimetric measurement is another method for determination of solvation processes of the stationary phases. Changes of the heat of immersion provide information about the surface accessibility for interaction with solvent molecules. The increase of the stationary phase coverage density reduces the free space between bonded chains and penetration of solvent between organic chains.

Original languageEnglish
Pages (from-to)620-625
Number of pages6
JournalJournal of Colloid and Interface Science
Volume349
Issue number2
DOIs
Publication statusPublished - Sep 2010

Fingerprint

Liquid chromatography
Adsorption
Organic solvents
Water
Solvation
Acetonitrile
Methanol
Isotherms
Sorption
Ligands
Molecules
Hot Temperature

Keywords

  • Excess isotherm
  • Heat of immersion
  • Microcalorimetry
  • Solvent adsorption
  • Stationary phase
  • Surface heterogeneity

ASJC Scopus subject areas

  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Colloid and Surface Chemistry

Cite this

Study of solvent adsorption on chemically bonded stationary phases by microcalorimetry and liquid chromatography. / Buszewski, Bogusław; Bocian, Szymon; Rychlicki, Gerhard; Vajda, Péter; Felinger, A.

In: Journal of Colloid and Interface Science, Vol. 349, No. 2, 09.2010, p. 620-625.

Research output: Contribution to journalArticle

Buszewski, Bogusław ; Bocian, Szymon ; Rychlicki, Gerhard ; Vajda, Péter ; Felinger, A. / Study of solvent adsorption on chemically bonded stationary phases by microcalorimetry and liquid chromatography. In: Journal of Colloid and Interface Science. 2010 ; Vol. 349, No. 2. pp. 620-625.
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