Study of Lewis acid accelerated palladium catalyzed C[sbnd]H activation

Orsolya Tischler, Szabolcs Kovács, Gábor Érsek, Péter Králl, János Daru, A. Stirling, Z. Novák

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Acceleration of palladium catalyzed C[sbnd]H activation by various Lewis Acids was demonstrated on the directed ortho-alkenylation and acylation of acetanilide and urea derivatives. The universality of this effect was investigated by the study of different palladium catalysts, directing groups in the aromatic substrates and versatile Lewis acids. Experiments were carried out to monitor the reactions and to compare the behavior and activity of different types of Lewis acids. Kinetic investigation revealed a rate determining C[sbnd]H activation step, and DFT studies were performed for the explanation of Lewis acid effect on C[sbnd]H activation.

Original languageEnglish
Pages (from-to)444-450
Number of pages7
JournalJournal of Molecular Catalysis A: Chemical
Volume426
DOIs
Publication statusPublished - Jan 1 2017

    Fingerprint

Keywords

  • C[sbnd]H activation
  • DFT studies
  • Lewis acid
  • palladium

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology
  • Physical and Theoretical Chemistry

Cite this