UNTERSUCHUNG DER IRRITATIVEN WIRKUNG DES DITHRANOLS MITTELS KAPILLARRESISTENZMESSUNG

Translated title of the contribution: Study of dithranol-induced irritation by means of capillary resistance measurements

L. Kemény, M. Csato, J. Nyiradi, M. Gabor, A. Dobozy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The effect of topically applied dithranol on the capillary resistance (CR) was studied both in healthy volunteers and in clinically unaffected skin of psoriatic patients. The CR of the psoriatic patients was significantly lower than that of the healthy persons. 0.10% and 0.25% dithranol ointment induced a significant decrease of CR in the skin of both groups. This decrease was prevented or at least reduced, if the patients had previously been treated with either the antihistamine clemastine or the cyclooxygenase-inhibitor indomethacin. The effect of dithranol on the CR was also moderated, if 5% coal tar had been added to the dithranol preparation.

Original languageGerman
Pages (from-to)34-40
Number of pages7
JournalH+G Zeitschrift fur Hautkrankheiten
Volume64
Issue number1
Publication statusPublished - 1989

Fingerprint

Capillary Resistance
Anthralin
Clemastine
Coal Tar
Skin
Cyclooxygenase Inhibitors
Histamine Antagonists
Ointments
Indomethacin
Healthy Volunteers

ASJC Scopus subject areas

  • Dermatology

Cite this

UNTERSUCHUNG DER IRRITATIVEN WIRKUNG DES DITHRANOLS MITTELS KAPILLARRESISTENZMESSUNG. / Kemény, L.; Csato, M.; Nyiradi, J.; Gabor, M.; Dobozy, A.

In: H+G Zeitschrift fur Hautkrankheiten, Vol. 64, No. 1, 1989, p. 34-40.

Research output: Contribution to journalArticle

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