ZUR UNTERSUCHUNG DER KOMPLEMENTFAKTOREN C3 UND C4 IN DER SYNOVIAL-FLUSSIGKEIT BEI RHEUMATISCHEN ERKRANKUNGEN

Translated title of the contribution: Study of C3 and C4 complement components of synovial fluids in connective tissue diseases

U. Boehm, K. Meretey, A. Falus

Research output: Contribution to journalArticle

Abstract

C3 and C4 levels and the relative concentration of C3 degradation products were measured in fifty pairs of synovial fluid (SF) and sera of patients who suffered from different connective tissue diseases. Inverse correlation between C4 level and C3 breakdown products were found in synovial fluids of different groups. Compared to the other groups of patients, the highest increase of C3 degradation was found in rheumatoid arthritis (RA) patients and it occurred in the SF all of these patients. In arthrosis cases no degradation of C3 was found. Of the seven investigated cases of ankylosing spondylitis only two showed some degree of activation of C3 in the SF. Our results suggest that the occurrence and degree of degradation of C3 complement component is a valuable laboratory parameter in the study of connective tissue diseases.

Original languageGerman
Pages (from-to)167-174
Number of pages8
JournalAllergie und Immunologie
Volume24
Issue number3
Publication statusPublished - 1978

Fingerprint

Complement C4
Connective Tissue Diseases
Synovial Fluid
Complement C3
Joint Diseases
Ankylosing Spondylitis
Rheumatoid Arthritis
Serum

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

ZUR UNTERSUCHUNG DER KOMPLEMENTFAKTOREN C3 UND C4 IN DER SYNOVIAL-FLUSSIGKEIT BEI RHEUMATISCHEN ERKRANKUNGEN. / Boehm, U.; Meretey, K.; Falus, A.

In: Allergie und Immunologie, Vol. 24, No. 3, 1978, p. 167-174.

Research output: Contribution to journalArticle

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