Study of cross-sectional and longitudinal distribution of some major and minor elements in the hair samples of haemodialysed patients with micro-PIXE

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Abstract

The concentration of Zn, K, Ca, Fe and Cl was determined in the hair samples of haemodialysed patients and healthy controls. Cross-sectional and longitudinal measurements were performed using the micro-PIXE method. The concentration changes of the above mentioned elements along the length of the hair and their cross-sectional distribution were studied. The effect of the washing procedure on the concentration of these elements has also been determined. The ability of the PIXE method was examined using Human Hair certified reference material (NCS DC 73347), and the results show that this method can be used to determine the concentration of the selected elements in the hair samples. We compared the results of the PIXE method with the results obtained from microwave digested reference material with the ICP-OES method. The, concentration ranges of Ca, Fe and Zn were similar in the patients and controls while the concentration ranges of Cl and K were different (controls: Ca, 135-1598; Cl, 394-2382; Fe, 6-51; K, 54-1055; Zn, 102-183 μg g-1; versus patients: Ca, 298-559; Cl, 2476-7821; Fe, 15-58; K, 327-2031; Zn, 96-163 μg g-1). The washing procedure highly affected the concentration of K and Cl (unwashed: K, 1164 ± 846; Cl, 6107 ± 1714 μg g-1; vermy washed: K, 497 ± 552; Cl, 3470 ± 1446 μg g-1). There were no differences between controls and patients in the cross-sectional distribution of the selected elements; the distribution of Cl was homogeneous, the Ca was concentrated in the outer layer of the hair while the distribution of K was nearly homogeneous with a slight increase at the outer layer.

Original languageEnglish
Pages (from-to)553-557
Number of pages5
JournalJournal of analytical atomic spectrometry
Volume14
Issue number4
DOIs
Publication statusPublished - Jan 1 1999
EventProceedings of the 1998 8th Solid Sampling Spectrometry Colloquim (CSSS) - Budapest, Hungary
Duration: Sep 1 1998Sep 4 1998

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

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