Studies on the presence of antibodies to EB virus and other herpesviruses in normal children and in infectious mononucleosis

L. Gergely, J. Czegledy, L. Vaczi, B. Szabó, L. Binder, A. Szalka

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Children free from infectious disease were examined by indirect immunofluorescence for antibodies to the intracellular capsid antigen of Epstein Barr virus (EBV). In the first year of life 46%, between 2 and 6 years of age 66%, and between 7 and 14 years 91% of the children proved positive. The corresponding percentages for antibodies to cytomegalovirus (CMV) and herpes simplex virus were about 50% irrespective of the children's age. Serum samples from 69 cases of infectious mononucleosis (IM) were tested for anti EBV antibodies. Of the 29 Paul Bunnell positive patients 22 had antibodies, 11 in titers over 1:80. Of the 40 Paul Bunnel negative cases only 21 had antibodies, 8 in high titers. Of the Paul Bunell negative cases, 73% had anti CMV antibodies, 32% in high titers. The respective percentages for the Paul Bunnell positive cases were 42% and 10%.

Original languageEnglish
Pages (from-to)75-82
Number of pages8
JournalActa Microbiologica Academiae Scientiarum Hungaricae
Volume22
Issue number2
Publication statusPublished - 1975

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Infectious Mononucleosis
Herpesviridae
Viruses
Antibodies
Cytomegalovirus
Human Herpesvirus 4
Capsid
Simplexvirus
Indirect Fluorescent Antibody Technique
Communicable Diseases
Anti-Idiotypic Antibodies
Antigens
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Studies on the presence of antibodies to EB virus and other herpesviruses in normal children and in infectious mononucleosis. / Gergely, L.; Czegledy, J.; Vaczi, L.; Szabó, B.; Binder, L.; Szalka, A.

In: Acta Microbiologica Academiae Scientiarum Hungaricae, Vol. 22, No. 2, 1975, p. 75-82.

Research output: Contribution to journalArticle

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