Studies on the occurrence of circulating immune complexes in vascular diseases

G. Füst, Éva Szondy, Judit Székely, Ildikó Nánai, S. Gerö

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

The presence of circulating immune complexes was studied in 347 samples of serum from 212 patients with various vascular diseases. Two quantitative methods (complement-consumption assay and C1q-solubility test) were used for the measurement of the concentration of the complexes. Immune complexes were detected in each group of patients tested (coronary arteriosclerosis, myocardial infarction, cerebral artery sclerosis, arteriosclerosis obliterans, phlebothrombosis, pulmonary infarction). A high proportion of positivity was recorded in myocardial infarction (in 43 patients out of the 94 tested) and in arteriosclerosis obliterans (7 out of 11 cases). The possible pathogenic role of the circulating immune complexes is discussed.

Original languageEnglish
Pages (from-to)181-190
Number of pages10
JournalAtherosclerosis
Volume29
Issue number2
DOIs
Publication statusPublished - Feb 1978

Keywords

  • Arteriosclerosis
  • C1q
  • Complement
  • Immune complexes
  • Phlebothrombosis
  • Vascular disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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