Studies on human hyperkeratotic oral mucosa kept in tissue and organ cultures

J. Bánóczy, O. Török

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Tissue from cases of leukoplakia, leukoedema exfoliativa (white sponge naevus) and oral lichen planus was studied in tissue and organ culture for 6-20 days. The structure of the explants was retained better in organ cultures than on plasma clot. In cultures from hyperkeratotic oral mucosa proliferation was observed. The excised oral mucosa retained its differentiation towards keratinization during the period of observation. During cultivation, keratinization increased in intensity and extent; this was most pronounced in hyperorthokeratotic leukoplakia and lichen planus, where keratin plates were formed; parakeratotic leukoplakia retained its character. In leukoedema exfoliativa, intracellular keratinization could be observed in the stratum spinosum. Malignant transformation was not observed in any culture.

Original languageEnglish
JournalArchives of Oral Biology
Volume15
Issue number2
DOIs
Publication statusPublished - 1970

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Leukoplakia
Organ Culture Techniques
Mouth Mucosa
Oral Lichen Planus
Lichen Planus
Nevus
Porifera
Keratins
Observation

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Studies on human hyperkeratotic oral mucosa kept in tissue and organ cultures. / Bánóczy, J.; Török, O.

In: Archives of Oral Biology, Vol. 15, No. 2, 1970.

Research output: Contribution to journalArticle

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