Studies on chemotherapeutics III. Synthesis and cyclisation of 5‐substituted‐4‐oxo‐1,4‐dihydro‐3‐pyridinecarbonyl‐semicarbazide and‐ thiosemicarbazide

Mária Balogh, István Hermecz, Zoltán Mészáros, Levente Pusztay

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

1,4‐Disubstituted‐semicarbazide and thiosemicarbazide derivatives were synthetized from 5‐substituted‐4‐oxo‐1,4‐dihydro‐3‐pyridinecarbohydrazides and cyclized to 3‐mercapto‐4H‐1,2,4‐triazoles. The obtained compounds could be S‐methylated with methyl iodide in methanol. The new compounds were tested for antibacterial and antifungal activities.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalJournal of Heterocyclic Chemistry
Volume17
Issue number1
DOIs
Publication statusPublished - Jan 1980

ASJC Scopus subject areas

  • Organic Chemistry

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